Target locus
This module executes a targeted analysis of the ABO locus on chromosome 9.
The inference relies on the simultaneous validation of three transition/deletion markers to resolve the phenotypic blood group.
Free analysis · ABO locus
Infer your ABO blood type from raw DNA.
A focused interpretation of rs8176719, rs8176746, and rs8176747 from supported commercial files, including Living DNA autosomal exports — with every marker call shown alongside the result.
Does 23andMe show your blood type?
No—23andMe does not currently provide a standard ABO blood-type report. If your downloaded raw data contains the required ABO markers, Genostruct can use them to estimate A, B, AB, or O. This is not clinical blood typing and does not determine Rh positive or negative status.
Run the ABO marker check
Choose the unmodified raw export from your provider. We inspect only the marker calls needed for this analysis.
Files are processed in-memory and never stored.
Drop your raw DNA file here
or.txt, .csv, .tsv, .zip, .gz · 30 MB max
Method note
How the three-marker inference works.
This module analyses the ABO locus on chromosome 9, validating three critical transition/deletion markers to resolve your phenotypic blood group.
Marker rs8176719
Identifies the 'O' allele deletion — a single-base deletion causing a frameshift and a non-functional enzyme.
When both copies carry this deletion, the result is blood type O.
Markers rs8176746 & rs8176747
Distinguish A and B alleles by detecting nucleotide transitions that alter enzyme substrate specificity.
Together they determine whether a functional allele produces the A or B antigen.
Reporting scope
Resolves A, B, AB, and O groups from raw genotype data.
Each marker call is validated for completeness and allele quality before the final inference.
Limitations
Common haplotypes, not every ABO allele.
The three-marker model resolves the common A, B, and O1 patterns. Rare O alleles and other ABO subtypes can require full gene sequencing, and Rh positive or negative is a separate blood-group system.
Primary evidence
Research behind the panel.
- ISBT Blood Group DatabaseOfficial allele nomenclature and variant catalogue
- Common ABO haplotype inferencers8176719, rs8176746, and rs8176747
- Long-read ABO characterisationWhy rare subtypes need more than three positions
Go beyond individual traits
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