Target Locus
This module executes a targeted analysis of the ABO locus on Chromosome 9.
The inference logic relies on the simultaneous validation of three critical transition/deletion markers to resolve the phenotypic blood group.
ABO blood type calculator
23andMe & AncestryDNA Blood Type Calculator
Upload your 23andMe or AncestryDNA raw file and receive a validated interpretation of the rs8176719, rs8176746, and rs8176747 markers. Genostruct explains each call so you can understand how the result was inferred.
Upload your raw DNA file
Securely parse the core ABO markers in seconds. Supported providers: 23andMe, AncestryDNA.
Files are processed in-memory and never stored.
Drop genomic data file here
or.txt, .zip ยท 25 MB max
ABO Blood Type Inference from Genetic Raw Data
This module analyses the ABO locus on Chromosome 9, validating three critical transition/deletion markers to resolve your phenotypic blood group.
Marker rs8176719
Identifies the 'O' allele deletion. A single base deletion (G) at this position causes a frameshift resulting in a non-functional enzyme.
When both copies carry this deletion, the result is blood type O.
Markers rs8176746 & rs8176747
Distinguishes between A and B alleles by detecting specific nucleotide transitions that alter enzyme substrate specificity.
These two markers work together to determine whether a functional allele produces the A or B antigen.
Reporting Scope
Resolves A, B, AB, and O groups from raw genotype data.
Each marker call is validated for completeness, allele quality, and expected genotype patterns before the final inference is made.